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Atorvastatin lowers coQ10 levels in patients at risk of cardiovascular disease
New method to make coenzyme Q10 more affordable
Boosting Omega-3 Intake May Help Protect the Heart, Mind and Body

Heart Health with Life Extension

Coenzyme Q10 | Omega-3 Fatty Acids | Endothelial Defense™ | more...

Coenzyme Q10
When it comes to achieving optimal results from your CoQ10 supplement, how much you absorb is of critical importance. Since 1983, Life Extension has continuously sought out the purest, most bioavailable CoQ10 available. Now, Japan's largest CoQ10 producer has patented a form of CoQ10 that offers unprecedented bioavailability—capable of increasing human blood levels up to 8 times more efficiently than the higher-absorption CoQ10 products on the market today.

In studies from Japan, this superior new form of CoQ10 has shown remarkable antiaging effects. In one study, it was 40 percent more effective than conventional CoQ10 in slowing markers of aging in middle-aged mice.2 In a study of aged rats, this new form of CoQ10 demonstrated anti-fatigue effects that were 2.5 times greater than conventional CoQ10 supplements.3

The reason this new form of CoQ10 is so effective is that scientists have succeeded for the first time in producing a stabilized ubiquinol capsule form of CoQ10. While CoQ10 exists in both ubiquinol and ubiquinone forms, the ubiquinol form has been shown to be vastly more bioavailable than conventional ubiquinone CoQ10. In a study measuring absorption in humans supplementing with 150 mg and 300 mg , far lower doses of ubiquinol CoQ10 produced blood plasma levels of CoQ10 that were equivalent to those produced by much higher doses of ubiquinone.4 In fact, it would take up to 8 times more ubiquinone than ubiquinol to raise CoQ10 blood levels to the same level.4

Omega-3 Fatty Acids
Studies associate the Mediterranean diet, rich in omega-3 fatty acids, olive oil, and antioxidant-rich fruits, vegetables, and herbs, with lowered cardiovascular risk and increased life span.5 Other studies support omega-3’s importance cardiovascular health.6-11 In fact, the FDA states that supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.

An enormous amount of scientific data documents the health risks associated with excess consumption of polyunsaturated fatty acids. While the polyunsaturated fats known as omega-6 fatty acids are essential to optimal health, most Americans and citizens of other Western nations consume far too many omega-6 polyunsaturated fatty acids and not enough omega-3 polyunsaturated fatty acids.

The omega-3 fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are found in abundance in fatty fish and some marine mammals, as well as in the algae (seaweed) upon which they feed. Based on the multiple health effects of omega-3 fatty acids, including its effects on the heart, the importance of DHA and EPA cannot be overstated.

Only Life Extension’s Super Omega-3 EPA/DHA with Sesame Lignans & Olive Fruit Extract contains the "healthy trio" of concentrated nutrients from fish oil, sesame seed oil and extra virgin olive oil. Super Omega-3 EPA/DHA with Sesame Lignans & Olive Fruit Extract contains twice as much EPA and DHA as conventional fish oil capsules.

Endothelial Defense™
Scientists have developed a breakthrough in the ability to maintain healthy endothelial function in aging arteries.  An orally active superoxide dismutase (SOD) derived from melons (called GliSODin®) has been clinically proven to support healthy arterial function and structure while boosting levels of the body’s most powerful natural antioxidant enzymes.  This patented SOD has a protective outer coating that prevents it from breaking down in the stomach’s acidic environment. This enables the SOD to be absorbed intact into the bloodstream.12,13

In a groundbreaking study, GliSODin® was shown to help support and improve vascular blood flow in middle-aged adults who had multiple risk factors for future cardiovascular problems.14

 

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References

1. Circulation. 2000 Oct 31;102(18):2284-99.
2. Exp Gerontol 2006 Feb;41(2):130-40.
3. Kaneka Corporation study. Treadmill test with the age rat at the age of 61-63 weeks. 2006.
4. Regul Toxicol Pharmacol. 2006 Aug 17; Absorption Comparison Using Different Form of CoQ10.
5. JAMA. 2004 Sep 22;292(12):1440-6.
6. Int J Epidemiol. 1997 Feb;26(1):155-9.
7. N Engl J Med. 2003 Jun 26;348(26):2599-608.
8. Br J Nutr. 2000 Dec;84 Suppl 2:S205-9.
9. BMJ. 1995 Dec 2;311(7018):1457-60.
10. JAMA. 2004 Sep 22;292(12):1433-9.
11. Am J Clin Nutr. 2000 Apr;71(4):987-92.
12. Phytother Res. 2004 Dec;18(12):957-62.
13. J Ethnopharmacol. 2004 Sep;94(1):67-75.
14. Allerg Immunol.(Paris). 2007 Feb;39(2):45-50.